Algorithms, Bioinformatics, Allostery, Drug Discovery, Computational Pharmaceutical Biochemistry, Computational Biology, Structural Biology, Mathematical Modelling and Robotics
A method for validation of NMR structures.
Manipulating GPCRs function with allostery (signal propagation) Mechanistic Insights into Allosteric Regulation of the A2A Adenosine G-Protein-Coupled Receptor by Physiological Cations, published in Nature Communication 2018 See Press Release
Evolution of Antibody Flexibility Repertoire Analysis of Antibody CDR-H3 Loops Suggests Affinity Maturation Does Not Typically Result in Rigidification, Published in Frontiers in Immunology 2018
The role of dimer asymmetry and protomer dynamics in enzyme catalysis, published in Science 2017. See Press Release. For video Click here
Characterizing structures of intrinsically disordered proteins in Alzheimer’s and neurodegenerative diseases. Published in PLOS ONE
